Major funding secured for genotyping

Feb 16, 2015 12:00 AM

In February 2015 the CKB was awarded a total of £5m from the MRC Newton Fund for further large-scale genotyping of China Kadoorie Biobank.

The Newton Fund - administered by several UK delivery partners - aims to strengthen research and innovation partnerships between the UK and emerging knowledge economies. The £5 million funding will cover the costs of genotyping up to 100,000 CKB participants using a custom-designed 700K SNP Affymetrix genome-wide array recently optimised for the Chinese population. The project will use a genotyping platform and procedures already fully established at BGI, Shenzhen, China and will take 2-3 years to complete. It is expected that this support will leverage funding from elsewhere to genotype larger numbers.

Genotyping data will complement the extensive range of exposure and disease outcome data already being collected and other multi-omics data to be generated from the stored biological samples. Together they will create a uniquely powerful resource that will underpin population health and biomedical research for the next decade and beyond. It will enhance research into disease aetiology, risk prediction and development of new therapies for major chronic diseases.