SNP genotyping study completed for 100,000 participants

Sep 27, 2013 2:00 PM

Genotyping of 384 genetic variants (SNPs) in 100,000 China Kadoorie Biobank participants has been completed at BGI-Shenzhen.

The SNPs were selected based on association with a range of chronic diseases (e.g. stroke, IHD, diabetes) and related phenotypes (e.g. blood pressure, adiposity, lung function) in previous large studies. Analyses in CKB participants will focus on using SNPs as tools to evaluate the causal relevance of risk factors for chronic diseases. For example a risk score consisting of SNPs associated with blood pressure can be used to evaluate the causal effect of blood pressure in different stroke subtypes.