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Use of genetic data to predict effects of vitamin D supplements on risk of diabetes

May 2, 2018 5:00 PM

Vitamin D is essential for healthy bones, but low blood levels of vitamin D have also been linked with higher risks of diabetes. Experts have debated whether low vitamin D status increases the risk of diabetes, or is just a marker of overall poor health. Researchers at Oxford University used Mendelian Randomisation to dissect the causal effect of vitamin D on risk of diabetes. This method uses genetic variants resulting in life-long differences in blood levels of vitamin D that can mimic the effect of a trial of vitamin D supplementation.