DPhil Programme

Please see the Nuffield Department of Population Health (NDPH) website for full information on the DPhil programme, applicaitons proceedures and projects available in other NDPH groups. 

Current CKB projects for October 2019 intake:

Accelerometer-measured physical activity, sedentary behaviour and sleep, and their associations with cardiometabolic risk factors in the China Kadoorie Biobank Supervisors: Derrick Bennett, Christiana Kartsonaki, Huaidong Du

Assessing effects of environmental exposures using novel personal exposure metrics on risk factors and major diseases Supervisors: Hubert Lam, Derrick Bennett, Zhengming Chen

Assessment of host and pathogen determinants of infection-related cancer and other chronic diseases inChinese adults Supervisors: Ling Yang, Iona Millwood, Derrick Bennett, Zhengming Chen

Burden and risk factors of infectious complications among Chinese adults with diabetes Supervisors: Fiona Bragg, Christiana Kartsonaki, Iona Millwood, Zhengming Chen

Causal relevance of reproductive factors for major chronic diseases in Chinese women Supervisors: Fiona Bragg, Iona Millwood, Kuang Lin, Zhengming Chen

Causes and consequences of frailty in older people in China Supervisors: Robert Clarke, Sofia Massa, Yiping Chen

Causes and consequences of heart failure in Chinese adults Supervisors: Robert Clarke, Derrick Bennett, Yiping Chen

Determinants and consequences of multi-morbidity associated with major cardio-metabolic diseases in China Supervisors: Fiona Bragg, Yiping Chen, Derrick Bennett

Developing novel genetic risk scores for prediction of cardiovascular disease Supervisors: Robert Clarke, Sofia Massa

Development and application of novel methods for large scale genetic studies in Chinese and UK populations Supervisors: Robin Walters, Kuang Lin

Lifestyle and genetic determinants of diabetic retinopathy and other retinal diseases among Chinese adults Supervisors: Huaidong Du, Fiona Bragg, Derrick Bennett

Lifestyle and genetic determinants of glaucoma in Chinese adults Supervisors: Huaidong Du, Fiona Bragg, Derrick Bennett

Phenome-wide association studies of functional genetic variants to validate drug targets Supervisors: Iona Millwood, Derrick Bennett, Zhengming Chen

Trans-ethnic genetics and genomics of major diseases  Supervisors: Robin Walters, Kuang Lin

 

Selected publications by recent and current CKB DPhil students:

Bragg F, Holmes MV, Iona A, Guo Y, Du HD, Chen YP, Bian Z, Yang L, Herrington W, Bennett DA, Turnbull I, Liu Y, Feng S, Chen JS, Clarke RJ, Collins R, Peto R, Li LM, Chen ZM. Association between diabetes and cause-specific mortality in rural and urban areas of China. JAMA 2017; 317(3):280-9. see also editorial Chan M. China's burgeoning epidemic of diabetes-associated mortality. JAMA 2017; 317(3):264-6

Bragg F, Li LM, Chen ZM. Urban-rural differences in diabetes-associated mortality in China-Reply. JAMA 2017; 317(16):1689

Bragg F, Li LM, Bennett DA, Guo Y, Lewington S, Bian Z, Yang L, Chen JS, Chen YP, Collins R, Peto R, Zhu B, Yin J, Hu X, Zhou L, Pan Y, Chen ZM. Association of random plasma glucose levels with the risk for cardiovascular disease among Chinese adults without known diabetes. JAMA Cardiol 2016; 1(7):813-23

Bragg F, Li LM, Yang L, Guo Y, Chen YP, Bian Z, Chen JS, Collins R, Peto R , Wang C, Dong C , Pan R, Zhou J, Xu X, Chen ZM. Risks and population burden of cardiovascular diseases associated with diabetes in China: a prospective study of 0.5 million adults. PLoS Med 2016; 13(7):e1002026

Bragg F, Li LM, Smith M, Guo Y, Chen YP, Millwood IY, Bian Z, Walters RG, Chen JS, Yang L, Collins R, Peto R, Lu Y, Yu B, Xie X, Lei Y, Luo GJ, Chen ZM. Associations of blood glucose and prevalent diabetes with risk of cardiovascular disease in 500,000 adult Chinese: the China Kadoorie Biobank. Diabet Med 2014; 31(5):540-51

Bragg F, Tung K, Guo Y, Iona A, Du HD, Holmes MV, Bian Z, Kartsonaki C, Chen YP, Yang L, Sun Q, Dong C, Chen JS, Collins R, Peto R, Li LM, Chen ZM. Associations of general and central adiposity with incident diabetes in Chinese men and women. Diabetes Care 2018; 41(3):494-502

Chan KH, Kurmi OP, Bennett DA, Yang L, Chen Y, Tan Y, Pei P, Zhong X, Chen J, Zhang J, Kan H, Peto R, Lam KBH, Chen ZM. Solid fuel use and risks of respiratory diseases: a cohort study of 280,000 Chinese never-smokers. Am J Respir Crit Care Med 2018 (in press)

Chan KH, Lam KBH, Kurmi OP, Guo Y, Bennett DA, Bian Z, Sherliker P, Chen JS, Li LM, Chen ZM. Trans-generational changes and rural-urban inequality in household fuel use and cookstove ventilation in China: A multi-region study of 0.5 million adults. Int J Hyg Environ Health 2017; 220(8):1370-81

Yu K, Qiu G, Chan KH, Lam KH, Kurmi OP, Bennett DA, Yu CQ, Pan A, Lv J, Guo Y, Bian Z, Yang L, Chen Y, Hu FB, Chen ZM, Li LM, Wu TC. Association of solid fuel use with risk of cardiovascular and all-cause mortality in rural China. JAMA 2018; 319(13):1351-61

Lacey B, Lewington S, Clarke RJ, Kong XL, Chen Y, Guo Y, Yang L, Bennett DA, Bragg F, Bian Z, Wang S, Zhang H, Chen J, Walters RG, Collins R, Peto R, Li LM, Chan ZM. Age-specific association between blood pressure and vascular and non-vascular chronic diseases in 0·5 million adults in China: a prospective cohort study. Lancet Glob Health 2018; 6(6):e641-9

Newell K, Kartsonaki C, Lam KBH, Kurmi OP. The cardiorespiratory health effects of gaseous ambient air pollution exposure in low and middle income countries: a systematic review and meta-analysis. Environmental Health 2018; 17(1): 41-54

Newell K, Kartsonaki C, Lam K, Kurmi O. The cardiorespiratory health effects of particulate ambient air pollution exposure in low-income and middle-income countries (LMICs): a systematic review and meta-analysis. Lancet Planet Health 2017; 1(19):e368–e80

Pang Y, Holmes MV, Guo Y, Yang L, Bian Z, Chen YP, Iona A, Millwood IY, Bragg F, Chen JS, Li LM, Kartsonaki C, Chen ZM. Smoking, alcohol and diet in relation to risk of pancreatic cancer in China: a prospective study of 0.5 million people. Cancer Med 2018; 7(1):229-39

Pang Y, Holmes MV, Kartsonaki C, Guo Y, Yang L, Bian Z, Chen YP, Bragg F, Iona A, Millwood IY, Chen JS, Li LM, Chen ZM. Young adulthood and adulthood adiposity in relation to incidence of pancreatic cancer: a prospective study of 0.5 million Chinese adults and a meta-analysis. J Epidemiol Community Health 2017; 71(11):1059-67

Pang Y, Kartsonaki C, Guo Y, Bragg F, Chen YP, Yang L, Bian Z, Bragg F, Millwood IY, Mao E, Li Y, Shi L, Chen J, Li LM, Holmes MV, Chen ZM. Adiposity and risks of colorectal and small intestine cancer in Chinese adults: a prospective study of 0.5 million people. Br J Cancer 2018; 119:248-50

Pang Y, Kartsonaki C, Guo Y, Bragg F, Yang L, Bian Z, Chen YP, Iona A, Millwood IY, Lv J, Yu CQ, Chen JS, Li LM, Holmes MV and Chen ZM. Diabetes, plasma glucose and incidence of pancreatic cancer: A prospective study of 0.5 million Chinese adults and a meta-analysis of 22 cohort studies. Int J Cancer 2017; 140(8):1781–8

Pang Y, Kartsonaki C, Guo Y, Chen Y, Yang L, Bian Z, Bragg F, Millwood IY, Shen L, Zhou S, Liu J, Chen J, Li L, Holmes MV, Chen Z. Diabetes, plasma glucose and incidence of colorectal cancer in Chinese adults: a prospective study of 0.5 million people. J Epidemiol Community Health; 2018; doi: 10.1136/jech-2018-210651

Pang Y, Kartsonaki C, Turnbull I, Guo Y, Clarke RJ, Chen Y, Bragg F, Yang L, Bian Z, Millwood IY, Hao J, Han X, Zang Y, Chen J, Li L, Holmes MV, Chen Z. Diabetes, plasma glucose and incidence of fatty liver, cirrhosis and liver cancer in Chinese: a prospective study of 0.5 million people. Hepatology 2018; doi:10.1002/hep.30083

Pang Y, Kartsonaki C, Turnbull I, Guo Y, Yang L, Bian Z, Chen YP, Millwood IY, Bragg F, Gong W, Xu Q, Kang Q, Chen J, Li LM, Holmes MV, Chen ZM. Metabolic and lifestyle risk factors for acute pancreatitis in Chinese adults: a prospective cohort study of 0.5 million people. PLoS Medicine 2018; 15(8):1-19